Dependency of endothelial cell loss on anterior chamber depth within first 4 years after implantation of iris-supported phakic intraocular lenses to treat high myopia

Shallow anterior chambers a possible contraindication for iris-fixated IOLs

Iris-fixated IOLs provide highly predictable refractive results, although shallow anterior chamber depths (ACD) may be a contraindication for the lenses, a new study shows. In 95 eyes of 52 highly myopic patients implanted with the Artisan phakic IOL, the mean spherical equivalent was −0.42 dioptres (D) and 72 eyes (76%) had an uncorrected distance visual acuity of 0.8 or better. There was a mean decrease in endothelial cell density (ECD) of 4.5% at one year and 11% after the fourth year. There was a significantly higher ECD loss after four years in patients with an ACD of less than 3.00mm than in those with an ACD greater than 3.40 mm, with 224 fewer endothelial cells per millimetre.

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