Similar five-year results with SMILE and FS-LASIK

The results of a prospective, comparative nonrandomised clinical study indicate that small incision lenticule extraction (SMILE) and LASIK with femtosecond laser-created flaps (FS‐LASIK) have similar efficacy, safety, predictability and long-term stability.

The study included 68 eyes of 37 patients that underwent SMILE and 55 eyes of 30 patients that underwent FS‐LASIK between December 2011 and January 2013. At a five-year follow-up, about 98% (49/50) of eyes in the SMILE group and 95% (39/41) in the FS‐LASIK group had a postoperative logMAR uncorrected distance visual acuity of 0.0 or better. The mean myopic regression was only −0.02 ± 0.39 D in the SMILE group and only −0.12 ± 0.32 D in the FS‐LASIK group. In agreement with some previous studies, SMILE induced less spherical aberration and more coma than FS‐LASIK.

In addition, in both SMILE‐treated and LASIK-treated eyes, coma and higher order aberrations remained stable from six months to five years postoperatively, and spherical aberration remained stable from three months to five years postoperatively.


Meiyan Li et al, “Five‐year results of small incision lenticule extraction (SMILE) and femtosecond laser LASIK (FS‐LASIK) for myopia”, Acta Ophthalmologica 2019, 97;3: e373-e380.

Source: Wiley

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